New England Biolabs (NEB) is seeking highly motivated and detail-oriented individual for a downstream protein manufacturing role as a Purification Scientist in a laboratory equipped with cutting edge technologies.
The successful candidate will execute downstream processes and perform in-process analytics. This role requires working in a fast-paced and collaborative environment to provide the highest quality products to the scientific community.
Primary Responsibilities :
Program, operate, and troubleshoot purification equipment at small / pilot scale using the GE AKTA platform including AKTA PURE, Pilot, Process, as well as Tangential Flow Filtration and Inline Buffer Dilution Skids
Represent commercial manufacturing needs in close working interaction with internal process development and management
Perform and analyze numerous in process enzymatic and DNA assays required during the purification process to develop pooling protocols
Apply creative problem solving to downstream processes to perform tasks more efficiently and effectively
Maintain accurate records. Effectively organize, interpret and present data to colleagues, cross functional teams and senior leadership
Advocate for new biopharma and information technologies to help advance downstream manufacturing
Required Qualifications and Experience :
Bachelor’s or advanced degree in Biology, Biochemistry, or a related field
Minimum 3 years of industry experience
Extensive knowledge of chromatography techniques including IEX, affinity, HIC, SEC and MMC
Hands on experience with downstream processing equipment and protocols including sanitization, general operation, troubleshooting, and associated manufacturing tasks
Experience operating protein purification equipment and knowledge of Unicorn software
Familiarity with techniques such as SDS PAGE, restriction digestion, capillary electrophoresis-based RNA, DNA and protein assays
Demonstrate precise bench skills to produce consistent and dependable data
Exceptional attention to detail and passion for problem solving with a developed sense of ownership and responsibility
Working knowledge of microbial fermentation and upstream processing a plus
New England Biolabs, Inc. is an Equal Opportunity / Affirmative Action Employer of Minorities, Females, Disabled and Protected Veterans and a participating employer in the Employment Verification (E-Verify) program.
More in-depth details of EEO are available .
If you need an accommodation for any part of the employment process because of a medical condition or disability, please send an email to or call 978-927-5054 to let us know the nature of your request.